Rukwa Region (Mkoa wa Rukwa in Swahili) covers 27,765 km² (10,720 sq mi), a land area comparable to Haiti. It is located in southwestern Tanzania, sharing borders with Katavi Region to the north, Songwe Region to the east, Zambia to the south, and Lake Tanganyika to the west, which separates Tanzania from the Democratic Republic of the Congo.
The regional capital is Sumbawanga, a developing urban center. As of the 2022 national census, Rukwa has a population of 1,540,519 people.
Rukwa consists of highland plateaus, deep valleys, and the western rift escarpments. The Ufipa Plateau dominates the region, providing fertile agricultural land. The region is also home to Lake Rukwa, an important water source for fishing and wildlife. The climate varies from temperate in the highlands to warm in the lowlands.